1.5k citations
- University of California, San FranciscoUS3 papers
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Showing 2013Show all
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q-bio.PE2013★ 1.5k cited
Ancient human genomes suggest three ancestral populations for present-day Europeans
Iosif Lazaridis, Nick Patterson, Alissa Mittnik +117
We sequenced genomes from a 7,000 year old early farmer from Stuttgart in Germany, an 8,000 year old hunter-gatherer from Luxembourg, and seven 8,000 year old hun…
q-bio.GN2013★ 174 cited
Integrating diverse datasets improves developmental enhancer prediction
Genevieve D. Erwin, Rebecca M. Truty, Dennis Kostka +2
Gene-regulatory enhancers have been identified by many lines of evidence, including evolutionary conservation, regulatory protein binding, chromatin modifications, and DNA sequence…
q-bio.GN2013
A Model-Based Analysis of GC-Biased Gene Conversion in the Human and Chimpanzee Genomes
John A. Capra, Melissa J. Hubisz, Dennis Kostka +2
GC-biased gene conversion (gBGC) is a recombination-associated process that favors the fixation of G/C alleles over A/T alleles. In mammals, gBGC is hypothesized to contribute to v…