781 citations
6 papers · 1 filter
Is there any sense in antisense editing?
Yossef Neeman, Dvir Dahary, Erez Y. Levanon +2
A number of recent studies have hypothesized that sense-antisense RNA transcript pairs create dsRNA duplexes that undergo extensive A-to-I RNA editing. Here we studied human and mo…
Evidence for abundant transcription of non-coding regions in the Saccharomyces cerevisiae genome
Moshe Havilio, Erez Y. Levanon, Galia Lerman +2
Background: Recent studies in a growing number of organisms have yielded accumulating evidence that a significant portion of the non-coding region in the genome is transcribed. We…
Evolutionarily conserved human targets of adenosine to inosine RNA editing
Erez Y. Levanon, Martina Hallegger, Yaron Kinar +5
A-to-I RNA editing by ADARs is a post-transcriptional mechanism for expanding the proteomic repertoire. Genetic recoding by editing was so far observed for only a few mammalian RNA…
Is abundant A-to-I RNA editing primate-specific?
Eli Eisenberg, Sergey Nemzer, Yaron Kinar +3
A-To-I RNA editing is common to all eukaryotes, associated with various neurological functions. Recently, A-to-I editing was found to occur abundantly in the human transcriptome. H…
Systematic identification of abundant A-to-I editing sites in the human transcriptome
Erez Y. Levanon, Eli Eisenberg, Rodrigo Yelin +10
RNA editing by members of the double-stranded RNA-specific ADAR family leads to site-specific conversion of adenosine to inosine (A-to-I) in precursor messenger RNAs. Editing by AD…
Human housekeeping genes are compact
Eli Eisenberg, Erez Y. Levanon
We identify a set of 575 human genes that are expressed in all conditions tested in a publicly available database of microarray results. Based on this common occurrence, the set is…