24 citations
- Dayananda Sagar UniversityIN13 papers
- Dayananda Sagar College of EngineeringIN7 papers
- Indian Space Research OrganisationIN7 papers
- Indian Institute of Space Science and TechnologyIN6 papers
- Northeastern UniversityUS2 papers
- Saudi Aramco (United States)US2 papers
- Tata Institute of Fundamental ResearchIN2 papers
- Ambedkar University DelhiIN1 paper
- Astronomical Observatory of CapodimonteIT1 paper
- Bhattadev UniversityIN1 paper
- Boston UniversityUS1 paper
- Colorado State UniversityUS1 paper
7 papers · 1 filter
Multi-ligand simultaneous docking of Carica papaya leaf phytochemicals, Carpaine and Rutin, reveals multi-mechanism inhibition of cancer proteins BCL-2 and WWP1
Merla Sudha, Asmita Saha, Belaguppa Manjunath Ashwin Desai +2
Cancer remains a major global health concern due to chemotherapy resistance and toxicity from high-dose treatments. To overcome these challenges, new therapeutic strategies targeti…
Predicting Endocrine Disruptors: A Deep Learning QSAR Model for Estrogen Receptor Activity
Belaguppa Manjunath Ashwin Desai, Shreyas Murthy, Bhoomika Sridhar +3
Endocrine-disrupting chemicals (EDCs) threaten human health, ecosystems, and biodiversity by interfering with hormonal signaling pathways conserved across vertebrates. Traditional…
Deep Learning-based QSAR Model for Therapeutic Strategies Targeting SmTGR Protein's Immune Modulating Role in Host-Parasite Interaction
Belaguppa Manjunath Ashwin Desai, Belaguppa Manjunath Anirudh, Kalyani S Biju +2
Schistosomiasis, a neglected tropical disease caused by Schistosoma parasites, remains a major global health challenge. The Schistosoma mansoni thioredoxin glutathione reductase (S…
Multi-Ligand Simultaneous Docking Analysis of Moringa Oleifera Phytochemicals Reveals Enhanced BCL-2 Inhibition via Synergistic Action
Asmita Saha, Belaguppa Manjunath Ashwin Desai, Pronama Biswas
Moringa oleifera, known for its medicinal properties, contains bioactive compounds such as polyphenols and flavonoids with diverse therapeutic potentials, including anti-cancer eff…
Prediction of Novel CXCR7 Inhibitors Using QSAR Modeling and Validation via Molecular Docking
Belaguppa Manjunath Ashwin Desai, Merla Sudha, Suvarna Ghosh +1
CXCR7, a G-protein-coupled chemokine receptor, has recently emerged as a key player in cancer progression, particularly in driving angiogenesis and metastasis. Despite its signific…
Computational Analysis using Multi-ligand Simultaneous Docking of Withaferin A and Garcinol Reveals Enhanced BCL-2 and AKT-1 Inhibition
Pronama Biswas, Dishali Mathur, Jinal Dinesh +2
Developing an effective medicine to combat cancer and elusive stem cells is crucial in the current scenario. Withaferin A and Garcinol, important phytoconstituents of Withania somn…