papers

Publications (9)

cs.AI2024

AI-based Anomaly Detection for Clinical-Grade Histopathological Diagnostics

Jonas Dippel, Niklas Prenißl, Julius Hense +10

While previous studies have demonstrated the potential of AI to diagnose diseases in imaging data, clinical implementation is still lagging behind. This is partly because AI models…

cs.CV2026

Beyond Attention Heatmaps: How to Get Better Explanations for Multiple Instance Learning Models in Histopathology

Mina Jamshidi Idaji, Julius Hense, Tom Neuhäuser +12

Multiple instance learning (MIL) has enabled substantial progress in computational histopathology, where a large amount of patches from gigapixel whole slide images are aggregated…

cs.LG2024

Do Histopathological Foundation Models Eliminate Batch Effects? A Comparative Study

Jonah Kömen, Hannah Marienwald, Jonas Dippel +1

Deep learning has led to remarkable advancements in computational histopathology, e.g., in diagnostics, biomarker prediction, and outcome prognosis. Yet, the lack of annotated data…

cs.CV2026

Symb-xMIL: Symbolic Explanations for Multiple Instance Learning in Digital Pathology

Yanqing Luo, Julius Hense, Niklas Prenißl +4

Explanations of multiple instance learning (MIL) models are widely used for validation and discovery in digital histopathology. Existing methods primarily rely on heatmaps that hig…

cs.LG2025

xMIL: Insightful Explanations for Multiple Instance Learning in Histopathology

Julius Hense, Mina Jamshidi Idaji, Oliver Eberle +7

Multiple instance learning (MIL) is an effective and widely used approach for weakly supervised machine learning. In histopathology, MIL models have achieved remarkable success in…

cs.CV2026

Mind the Gap: Continuous Magnification Sampling for Pathology Foundation Models

Alexander Möllers, Julius Hense, Florian Schulz +3

In histopathology, pathologists examine both tissue architecture at low magnification and fine-grained morphology at high magnification. Yet, the performance of pathology foundatio…