6 papers
Symb-xMIL: Symbolic Explanations for Multiple Instance Learning in Digital Pathology
Yanqing Luo, Julius Hense, Niklas PreniÃl +4
Explanations of multiple instance learning (MIL) models are widely used for validation and discovery in digital histopathology. Existing methods primarily rely on heatmaps that hig…
In-Context Multiple Instance Learning
Alexander Möllers, Marvin Sextro, Julius Hense +2
Multiple Instance Learning (MIL) addresses problems where supervision is available at the level of bags of instances and has been successfully applied in fields ranging from comput…
Beyond Attention Heatmaps: How to Get Better Explanations for Multiple Instance Learning Models in Histopathology
Mina Jamshidi Idaji, Julius Hense, Tom Neuhäuser +12
Multiple instance learning (MIL) has enabled substantial progress in computational histopathology, where a large amount of patches from gigapixel whole slide images are aggregated…
Towards Robust Foundation Models for Digital Pathology
Jonah Kömen, Edwin D. de Jong, Julius Hense +9
Biomedical Foundation Models (FMs) are rapidly transforming AI-enabled healthcare research and entering clinical validation. However, their susceptibility to learning non-biologica…
MeDi: Metadata-Guided Diffusion Models for Mitigating Biases in Tumor Classification
David Jacob Drexlin, Jonas Dippel, Julius Hense +4
Deep learning models have made significant advances in histological prediction tasks in recent years. However, for adaptation in clinical practice, their lack of robustness to vary…
xMIL: Insightful Explanations for Multiple Instance Learning in Histopathology
Julius Hense, Mina Jamshidi Idaji, Oliver Eberle +7
Multiple instance learning (MIL) is an effective and widely used approach for weakly supervised machine learning. In histopathology, MIL models have achieved remarkable success in…