4 papers · 1 filter
CoMMiT: Co-informed inference of microbiome-metabolome interactions via transfer learning
Leiyue Li, Chenglong Ye, Tim Randolph +5
Recent multi-omic microbiome studies enable integrative analysis of microbes and metabolites, uncovering their associations with various host conditions. Such analyses require mult…
Microbial correlation: a semi-parametric model for investigating microbial co-metabolism
Haoran Shi, Yue Wang, Dan Cheng
The gut microbiome plays a crucial role in human health, yet the mechanisms underlying host-microbiome interactions remain unclear, limiting its translational potential. Recent mic…
Direct estimation and inference of higher-level correlations from lower-level measurements with applications in gene-pathway and proteomics studies
Yue Wang, Haoran Shi
This paper tackles the challenge of estimating correlations between higher-level biological variables (e.g., proteins and gene pathways) when only lower-level measurements are dire…
Integration of multiview microbiome data for deciphering microbiome-metabolome-disease pathways
Lei Fang, Yue Wang, Chenglong Ye
The intricate interplay between host organisms and their gut microbiota has catalyzed research into the microbiome's role in disease, shedding light on novel aspects of disease pat…