2 papers
stat.AP2025
BACTA-GPT: An AI-Based Bayesian Adaptive Clinical Trial Architect
Krishna Padmanabhan, Danny Baker
Bayesian adaptive clinical trials offer a flexible and efficient alternative to traditional fixed-design trials, but their implementation is often hindered by the complexity of Bay…
stat.ME2025
Statistical Design and Planning of an Adaptive Trial using Hierarchical Composite Outcomes: A Practical example
Krishna Padmanabhan, Cyrus Mehta
Hierarchical composite endpoints, such as those analyzed using the Finkelstein-Schoenfeld (FS) statistic, are increasingly used in clinical trials for their ability to incorporate…