4 papers
Spatially-Structured Models of Viral Dynamics: A Scoping Review
Thomas Williams, James M. McCaw, James M. Osborne
There is growing recognition in both the experimental and modelling literature of the importance of spatial structure to the dynamics of viral infections in tissues. Aided by the e…
Accounting for the geometry of the respiratory tract in viral infections
Thomas Williams, James M. McCaw, James M. Osborne
Increasingly, experimentalists and modellers alike have come to recognise the important role of spatial structure in infection dynamics. Almost invariably, spatial computational mo…
Investigation of P. Vivax Elimination via Mass Drug Administration
Md Nurul Anwar, James M. McCaw, Alexander E. Zarebski +2
Plasmodium vivax is the most geographically widespread malaria parasite due to its ability to remain dormant (as a hypnozoite) in the human liver and subsequently reactivate. Given…
Spatial information allows inference of the prevalence of direct cell-to-cell viral infection
Thomas Williams, James M. McCaw, James Osborne
The role of direct cell-to-cell spread in viral infections - where virions spread between host and susceptible cells without needing to be secreted into the extracellular environme…