550 citations · 1.1k across the 5 of their papers we have counts for
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Conformational dynamics of a single protein monitored for 24 hours at video rate
Weixiang Ye, Markus Götz, Sirin Celiksoy +6
We use plasmon rulers to follow the conformational dynamics of a single protein for up to 24 h at a video rate. The plasmon ruler consists of two gold nanospheres connected by a si…
Precision and accuracy of single-molecule FRET measurements - a worldwide benchmark study
Björn Hellenkamp, Sonja Schmid, Olga Doroshenko +50
Single-molecule Förster resonance energy transfer (smFRET) is increasingly being used to determine distances, structures, and dynamics of biomolecules in vitro and in vivo. However…
Efficient use of single molecule time traces to resolve kinetic rates, models and uncertainties
Sonja Schmid, Thorsten Hugel
Single molecule time traces reveal the time evolution of unsynchronized kinetic systems. Especially single molecule Förster resonance energy transfer (smFRET) provides access to en…
Experiment-friendly kinetic analysis of single molecule data in and out of equilibrium
Sonja Schmid, Markus Götz, Thorsten Hugel
We present a simple and robust technique to extract kinetic rate models and thermodynamic quantities from single molecule time traces. SMACKS (Single Molecule Analysis of Complex K…