550 citations · 651 across the 4 of their papers we have counts for
5 papers
The known unknowns of the Hsp90 chaperone
Laura-Marie Silbermann, Benjamin Vermeer, Sonja Schmid +2
Molecular chaperones are vital proteins that maintain protein homeostasis by assisting in protein folding, activation, degradation, and stress protection. Among them, heat-shock pr…
Nanopores -- a Versatile Tool to Study Protein Dynamics
Sonja Schmid, Cees Dekker
Proteins are the active working horses in our body. These biomolecules perform all vital cellular functions from DNA replication and general biosynthesis to metabolic signaling and…
Precision and accuracy of single-molecule FRET measurements - a worldwide benchmark study
Björn Hellenkamp, Sonja Schmid, Olga Doroshenko +50
Single-molecule Förster resonance energy transfer (smFRET) is increasingly being used to determine distances, structures, and dynamics of biomolecules in vitro and in vivo. However…
Efficient use of single molecule time traces to resolve kinetic rates, models and uncertainties
Sonja Schmid, Thorsten Hugel
Single molecule time traces reveal the time evolution of unsynchronized kinetic systems. Especially single molecule Förster resonance energy transfer (smFRET) provides access to en…
Experiment-friendly kinetic analysis of single molecule data in and out of equilibrium
Sonja Schmid, Markus Götz, Thorsten Hugel
We present a simple and robust technique to extract kinetic rate models and thermodynamic quantities from single molecule time traces. SMACKS (Single Molecule Analysis of Complex K…