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physics.med-ph2026

First-in-human quantum entanglement imaging

Pawel Moskal, Deepak Kumar, Sushil Sharma +37

Annihilation photons are quantum-entangled in polarization, a phenomenon that has not been exploited in medical diagnostics so far. We present the first in vivo imaging of the degr…

physics.med-ph2026

First Positronium Lifetime Imaging using Mn and Co with a plastic-based PET scanner

Manish Das, Sushil Sharma, Ermias Yitayew Beyene +45

Positronium Lifetime Imaging (PLI) extends positron emission tomography by using the lifetime of positronium atoms as a probe of tissue molecular architecture. In this work, we rep…

physics.med-ph2026

First ex-vivo positronium imaging of tissues with modular J-PET scanner using Sc radionuclide

Karol Kubat, Manish Das, Sushil Sharma +41

This study presents the first ex-vivo positronium imaging of human tissues using the modular J-PET scanner with the Sc radionuclide. The Sc isotope was produced via t…

physics.med-ph2026

Feasibility study of the positronium lifetime imaging with the Biograph Vision Quadra and J-PET tomographs

Szymon Parzych, Szymon Niedźwiecki, Ermias Yitayew Beyene +39

Background: After its first ex-vivo and in-vivo demonstration, Positronium Lifetime Imaging (PLI) has received considerable interest as a potential new diagnostic biomarker. High s…

physics.med-ph2025

First positronium imaging using Sc with the J-PET scanner: a case study on the NEMA-Image Quality phantom

Manish Das, Sushil Sharma, Aleksander Bilewicz +41

Positronium Lifetime Imaging (PLI), an emerging extension of conventional positron emission tomography (PET) imaging, offers a novel window for probing the submolecular properties…