123 citations · 301 across the 20 of their papers we have counts for
4 papers · 1 filter
Network estimation in State Space Model with L1-regularization constraint
Anani Lotsi, Ernst Wit
Biological networks have arisen as an attractive paradigm of genomic science ever since the introduction of large scale genomic technologies which carried the promise of elucidatin…
State-space modeling of dynamic genetic networks
Anani Lotsi, Ernst Wit
The genomic reality is a highly complex and dynamic system. The recent development of high-throughput technologies has enabled researchers to measure the abundance of many genes (i…
High dimensional Sparse Gaussian Graphical Mixture Model
Anani Lotsi, Ernst Wit
This paper considers the problem of networks reconstruction from heterogeneous data using a Gaussian Graphical Mixture Model (GGMM). It is well known that parameter estimation in t…
Joint modelling of ChIP-seq data via a Markov random field model
Yanchun Bao, Veronica Vinciotti, Ernst Wit +1
Chromatin ImmunoPrecipitation-sequencing (ChIP-seq) experiments have now become routine in biology for the detection of protein binding sites. In this paper, we present a Markov ra…