246 citations · 246 across the 2 of their papers we have counts for
3 papers
Influence of water models on water movement through AQP1
Miguel A. Gonzalez, Alberto Zaragoza, Charlotte I. Lynch +2
Water diffusion through membrane proteins is a key aspect of cellular function. Essential processes of cellular metabolism are driven by osmotic pressure, which depends on water ch…
Opening a hydrophobic gate: the nicotinic acetylcholine receptor as an example
Sarah E. Rogers, Kaihsu Tai, Oliver Beckstein +1
To what extent must a hydrophobic gate expand for the channel to count as open? We address this question using the nicotinic acetylcholine receptor (nAChR) as the exemplar. The nAC…
The influence of geometry, surface character and flexibility on the permeation of ions and water through biological pores
Oliver Beckstein, Mark S. P. Sansom
A hydrophobic constriction site can act as an efficient barrier to ion and water permeation if its diameter is less than the diameter of an ion's first hydration shell. This hydrop…