2 papers
q-bio.BM2025
Predicting mutational effects on protein binding from folding energy
Arthur Deng, Karsten Householder, Fang Wu +3
Accurate estimation of mutational effects on protein-protein binding energies is an open problem with applications in structural biology and therapeutic design. Several deep learni…
cs.LG2025
Restructuring Vector Quantization with the Rotation Trick
Christopher Fifty, Ronald G. Junkins, Dennis Duan +5
Vector Quantized Variational AutoEncoders (VQ-VAEs) are designed to compress a continuous input to a discrete latent space and reconstruct it with minimal distortion. They operate…