activity
20172025
most citedTheoretical Perspectives on Biological Machines

91 citations · 126 across the 8 of their papers we have counts for

collaborators

9 papers

cond-mat.soft2025

Droplet growth, Ostwald's rule, and emergence of order in Fused in Sarcoma

Farkhad Maksudov, Mauro L. Mugnai, Laura Dominguez +2

The low complexity domain of Fused in Sarcoma (FUS-LC consisting of 214 residues) undergoes phase separation, resulting in a dense liquid-like phase that forms early and slowly mat…

cond-mat.soft2024

Inter-Species Interactions in Dual, Fibrous Gel Enable Control of Gel Structure and Rheology

Mauro L Mugnai, Rose Tchuenkam Batoum, Emanuela Del Gado

Natural and synthetic multi-component gels display emergent properties, which implies that they are more than just the sum of their components. This warrants the investigation of t…

q-bio.BM2023

Conformational Fluctuations and Phases in Fused in Sarcoma (FUS) Low-Complexity Domain

D. Thirumalai, Abhinaw Kumar, Debayan Chakraborty +2

The well known phenomenon of phase separation in synthetic polymers and proteins has become a major topic in biophysics because it has been invoked as a mechanism of compartment fo…

physics.bio-ph2021★ 25 cited

Information flow, Gating, and Energetics in dimeric molecular motors

Ryota Takaki, Mauro L. Mugnai, D. Thirumalai

Molecular motors belonging to the kinesin and myosin super family hydrolyze ATP by cycling through a sequence of chemical states. These cytoplasmic motors are dimers made up of two…

cond-mat.soft2021

On the emergence of orientational order in folded proteins with implications for allostery

Debayan Chakraborty, Mauro Lorenzo Mugnai, D. Thirumalai

The beautiful structures of single and multi-domain proteins are clearly ordered in some fashion but cannot be readily classified using group theory methods that are successfully u…

cond-mat.soft2019★ 9 cited

Fragile-to-Strong Crossover, growing length scales, and dynamic heterogeneity in Wigner Glasses

Hyun Woo Cho, Mauro L. Mugnai, T. R. Kirkpatrick +1

Colloidal particles, which are ubiquitous, have become ideal testing grounds for the structural glass transition (SGT) theories. In these systems glassy behavior is manifested as t…

physics.bio-ph2019★ 91 cited

Theoretical Perspectives on Biological Machines

Mauro L. Mugnai, Changbong Hyeon, Michael Hinczewski +1

Many biological functions are executed by molecular machines, which consume energy and convert it into mechanical work. Biological machines have evolved to transport cargo, facilit…

q-bio.SC2019

How kinesin waits for ATP affects the nucleotide and load dependence of the stepping kinetics

Ryota Takaki, Mauro L. Mugnai, Yonathan Goldtzvik +1

Dimeric molecular motors walk on polar tracks by binding and hydrolyzing one ATP per step. Despite tremendous progress, the waiting state for ATP binding in the well-studied kinesi…

cond-mat.stat-mech2017★ 1 cited

Giant Casimir non-equilibrium forces drive coil to globule transition in polymers

Himadri S. Samanta, Mauro L. Mugnai, T. R. Kirkpatrick +1

We develop a theory to probe the effect of non-equilibrium fluctuation-induced forces on the size of a polymer confined between two horizontal thermally conductive plates subject t…