activity
20172019
most citedBroad pore lifetime distributions: A fundamental concept for cell electroporation

2 citations · 2 across the 5 of their papers we have counts for

collaborators

5 papers

physics.bio-ph2019

Biophysics-based critique of the assisted discharge mechanism hypothesis

Julie V. Stern, Thiruvallur R. Gowrishankar, Kyle C. Smith +1

Cell experiments with large, short electric field pulses of opposite polarity reveal a remarkable phenomenon: Bipolar cancellation (BPC). Typical defining experiments involve quant…

q-bio.SC2018

Nanopore occlusion: A biophysical mechanism for bipolar cancellation in cell membranes

Thiruvallur R. Gowrishankar, Julie V. Stern, Kyle C. Smith +1

Extraordinarily large but short electric field pulses are reported by many experiments to cause bipolar cancellation (BPC). This unusual cell response occurs if a first pulse is fo…

physics.bio-ph2017

Solute transport within single pores post-pulse

Julie V. Stern, Thiruvallur R. Gowrishankar, James C. Weaver

We present results of studying the post-pulse transport properties of single pores. Single pores exhibit active transport (drift), and not just passive transport (diffusion) at ear…

physics.bio-ph2017

Electroporation dynamics for different pore lifetimes based on the standard model

Thiruvallur R. Gowrishankar, Julie V. Stern, James C. Weaver

Standard model of electropration (EP) has long emphasized a single pore lifetime to explain post-pulse transport across cell membranes. However, pore lifetimes estimated from molec…

physics.bio-ph2017★ 2 cited

Broad pore lifetime distributions: A fundamental concept for cell electroporation

Julie V. Stern, Thiruvallur R. Gowrishankar, Kyle C. Smith +1

We describe a concept that has the potential to change how we think about the underlying mechanisms of cell membrane electroporation (EP). Prior experimental, theoretical and model…