136 citations · 347 across the 13 of their papers we have counts for
14 papers
Nanoscale Protein Diffusion in Supercooled Cryoprotectant Solutions
Maddalena Bin, Anita Girelli, Mariia Filianina +15
Vitrification during cryopreservation requires a quantitative understanding of protein transport in deeply supercooled cryoprotectant solutions, yet direct measurements at molecula…
(Dis-)appearance of liquid-liquid phase transitions in a heterogeneous activated patchy particle model and experiment
Furio Surfaro, Peixuan Liang, Hadra Banks +3
The ion-activated patchy particle model is an important theoretical framework to investigate the phase behaviour of globular proteins in the presence of multivalent ions. In this w…
Depletion-Induced Interactions Modulate Nanoscale Protein Diffusion in Polymeric Crowder Solutions
Michelle Dargasz, Nimmi Das Anthuparambil, Sebastian Retzbach +26
Macromolecular crowding plays a crucial role in modulating protein dynamics in cellular and in vitro environments. Polymeric crowders such as dextran and Ficoll are known to induce…
A pipeline for Megahertz X-ray Photon Correlation Spectroscopy on soft matter samples at the MID instrument of European XFEL
Aliaksandr Leonau, Felix Brausse, James Wrigley +27
In this paper we present the experimental protocol and data processing framework for Megahertz X-ray Photon Correlation Spectroscopy (MHz-XPCS) experiments on soft matter samples,…
Softness and Hydrodynamic Interactions Regulate Lipoprotein Transport in Crowded Yolk Environments
Nimmi Das Anthuparambil, Michelle Dargasz, Sonja Timmermann +27
Low-density lipoproteins (LDLs) serve as nutrient reservoirs in egg yolk for embryonic development and as promising drug carriers. Both roles critically depend on their mobility in…
Coherent X-rays reveal anomalous molecular diffusion and cage effects in crowded protein solutions
Anita Girelli, Maddalena Bin, Mariia Filianina +38
Understanding protein motion within the cell is crucial for predicting reaction rates and macromolecular transport in the cytoplasm. A key question is how crowded environments affe…
The ion activated attractive patchy particles model and its application to the liquid-vapour phase transitions
Furio Surfaro, Fajun Zhang, Frank Schreiber +1
Patchy particles are an intriguing subject of study and indeed a model system in the field of soft matter physics. In recent years, patchy particle models have been applied to desc…
An alternative approach to the osmotic second virial coefficient of protein solutions and its application to liquid liquid phase separation
Furio Surfaro, Ralph Maier, Kai-Florian Pastryk +3
The osmotic second virial coefficient B2 is an important parameter to describe the interactions and phase behavior of protein solutions, including colloidal systems and macromolecu…
On the analysis of two-time correlation functions: equilibrium vs non-equilibrium systems
Anastasia Ragulskaya, Vladimir Starostin, Fajun Zhang +2
X-ray photon correlation spectroscopy (XPCS) is a powerful tool for the investigation of dynamics covering a broad range of time and length scales. The two-time correlation functio…
Resolving molecular diffusion and aggregation of antibody proteins with megahertz X-ray free-electron laser pulses
Mario Reiser, Anita Girelli, Anastasia Ragulskaya +26
X-ray free-electron lasers (XFELs) with megahertz repetition rate can provide novel insights into structural dynamics of biological macromolecule solutions. However, very high dose…
Interplay between Kinetics and Dynamics of Liquid-Liquid Phase Separation in a Protein Solution Revealed by Coherent X-ray Spectroscopy
Anastasia Ragulskaya, Nafisa Begam, Anita Girelli +7
Microscopic dynamics of complex fluids in the early stage of spinodal decomposition (SD) is strongly intertwined with the kinetics of structural evolution, which makes a quantitati…
Multivalent Ion-Activated Protein Adsorption Reflecting Bulk Reentrant Behavior
Madeleine R. Fries, Daniel Stopper, Michal K. Braun +7
Protein adsorption at the solid-liquid interface is an important phenomenon that often can be observed as a first step in biological processes. Despite its inherent importance, sti…
Interplay of pH and Binding of Multivalent Metal Ions: Charge Inversion and Reentrant Condensation in Protein Solutions
Felix Roosen-Runge, Benjamin S. Heck, Fajun Zhang +2
Tuning of protein surface charge is a fundamental mechanism in biological systems. Protein charge is regulated in a physiological context by pH and interaction with counterions. We…
Viscosity and Diffusion: Crowding and Salt Effects in Protein Solutions
Marco Heinen, Fabio Zanini, Felix Roosen-Runge +9
We report on a joint experimental-theoretical study of collective diffusion in, and static shear viscosity of solutions of bovine serum albumin (BSA) proteins, focusing on the depe…