activity
20112021
most citedAn adaptively weighted statistic for detecting differential gene expression when combining multiple transcriptomic studies

121 citations · 205 across the 12 of their papers we have counts for

collaborators

12 papers

stat.ME2021

Heavy-tailed distribution for combining dependent -values with asymptotic robustness

Yusi Fang, George C. Tseng, Chung Chang

The issue of combining individual -values to aggregate multiple small effects is prevalent in many scientific investigations and is a long-standing statistical topic. Many class…

q-bio.QM2021★ 1 cited

Outcome-guided Sparse K-means for Disease Subtype Discovery via Integrating Phenotypic Data with High-dimensional Transcriptomic Data

Lingsong Meng, Dorina Avram, George Tseng +1

The discovery of disease subtypes is an essential step for developing precision medicine, and disease subtyping via omics data has become a popular approach. While promising, subty…

stat.ME2020

Outcome-Guided Disease Subtyping for High-Dimensional Omics Data

Peng Liu, Yusi Fang, Zhao Ren +2

High-throughput microarray and sequencing technology have been used to identify disease subtypes that could not be observed otherwise by using clinical variables alone. The classic…

stat.ML2019★ 2 cited

A sparse negative binomial mixture model for clustering RNA-seq count data

Tanbin Rahman, Yujia Li, Tianzhou Ma +2

Clustering with variable selection is a challenging yet critical task for modern small-n-large-p data. Existing methods based on sparse Gaussian mixture models or sparse K-means pr…

stat.ME2019★ 1 cited

Simultaneous Estimation of Number of Clusters and Feature Sparsity in Clustering High-Dimensional Data

Yujia Li, Xiangrui Zeng, Chien-Wei Lin +1

Estimating the number of clusters (K) is a critical and often difficult task in cluster analysis. Many methods have been proposed to estimate K, including some top performers using…

math.ST2019★ 2 cited

Properties of adaptively weighted Fisher's method

Yusi Fang, Shaowu Tang, Zhiguang Huo +2

Meta-analysis is a statistical method to combine results from multiple clinical or genomic studies with the same or similar research problems. It has been widely use to increase st…