2 papers
q-bio.QM2025
KinDEL: DNA-Encoded Library Dataset for Kinase Inhibitors
Benson Chen, Tomasz Danel, Gabriel H. S. Dreiman +18
DNA-Encoded Libraries (DELs) represent a transformative technology in drug discovery, facilitating the high-throughput exploration of vast chemical spaces. Despite their potential,…
q-bio.QM2024
Compositional Deep Probabilistic Models of DNA Encoded Libraries
Benson Chen, Mohammad M. Sultan, Theofanis Karaletsos
DNA-Encoded Library (DEL) has proven to be a powerful tool that utilizes combinatorially constructed small molecules to facilitate highly-efficient screening assays. These selectio…