activity
20032023
most citedAgent-Based Modeling of Host-Pathogen Systems: The Successes and Challenges

209 citations · 660 across the 12 of their papers we have counts for

collaborators

12 papers

q-bio.QM2023★ 13 cited

A closer look at parameter identifiability, model selection and handling of censored data with Bayesian Inference in mathematical models of tumour growth

Jamie Porthiyas, Daniel Nussey, Catherine A. A. Beauchemin +3

Mathematical models (MMs) are a powerful tool to help us understand and predict the dynamics of tumour growth under various conditions. In this work, we use 5 MMs with an increasin…

q-bio.CB2021

Quantifying the relative contribution of free virus and cell-to-cell transmission routes to the propagation of hepatitis C virus infections in vitro using an agent-based model

Kenneth Blahut, Christian Quirouette, Jordan J. Feld +2

Experiments have shown that hepatitis C virus (HCV) infections in vitro disseminate both distally via the release and diffusion of cell-free virus through the medium, and locally v…

q-bio.QM2021★ 53 cited

Time to revisit the endpoint dilution assay and to replace TCID and PFU as measures of a virus sample's infection concentration

Daniel Cresta, Donald C. Warren, Christian Quirouette +4

The infectivity of a virus sample is measured by the infections it causes, via a plaque or focus forming assay (PFU or FFU) or an endpoint dilution (ED) assay (TCID, CCID$_{…

astro-ph.HE2020★ 9 cited

The maximum energy of shock-accelerated electrons in a microturbulent magnetic field

Donald C. Warren, Catherine A. A. Beauchemin, Maxim V. Barkov +1

Relativistic shocks propagating into a medium with low magnetization are generated and sustained by small-scale but very strong magnetic field turbulence. This so-called "microturb…

q-bio.CB2020★ 19 cited

Quantification of Ebola virus replication kinetics in vitro

Laura E. Liao, Jonathan Carruthers, Sophie J. Smither +13

Mathematical modelling has successfully been used to provide quantitative descriptions of many viral infections, but for the Ebola virus, which requires biosafety level 4 facilitie…

q-bio.CB2019★ 77 cited

A mathematical model describing the localization and spread of influenza A virus infection within the human respiratory tract

Christian Quirouette, Nada P. Younis, Micaela B. Reddy +1

Within the human respiratory tract (HRT), viruses diffuse through the periciliary fluid (PCF) bathing the epithelium, and travel upwards via advection towards the nose and mouth, a…