194 citations · 475 across the 4 of their papers we have counts for
4 papers
Using a hydrogen-bond index to predict the gene-silencing efficiency of siRNA based on the local structure of mRNA
Kathy Q. Luo, Donald C. Chang
The gene silencing effect of short interfering RNA (siRNA) is known to vary strongly with the targeted position of the mRNA. A number of hypotheses have been suggested to explain t…
Spin Echo Studies on Cellular Water
D. C. Chang, C. F. Hazlewood, B. L. Nichols +1
Previous studies indicated that the physical state of cellular water could be significantly different from pure liquid water. To experimentally investigate this possibility, we con…
Distinction between the Preneoplastic and Neoplastic State of Murine Mammary Glands by spin-echo NMR
C. F. Hazlewood, D. C. Chang, D. Medina +2
We have, using spin-echo nuclear magnetic resonance spectroscopy, measured the relaxation times and diffusion coefficient of water protons in primary mammary adenocarcinomas of mic…
Using biophotonics to study signaling mechanisms in a single living cell
Donald C. Chang
To illustrate the power of the biophysical approach in solving important problems in life science, I present here one of our current research projects as an example. We have develo…