most citedUsing a hydrogen-bond index to predict the gene-silencing efficiency of siRNA based on the local structure of mRNA

194 citations · 194 across the 1 of their papers we have counts for

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physics.bio-ph2017★ 194 cited

Using a hydrogen-bond index to predict the gene-silencing efficiency of siRNA based on the local structure of mRNA

Kathy Q. Luo, Donald C. Chang

The gene silencing effect of short interfering RNA (siRNA) is known to vary strongly with the targeted position of the mRNA. A number of hypotheses have been suggested to explain t…