activity
20112025
most citedMachine Learning Methods in the Computational Biology of Cancer

37 citations · 48 across the 15 of their papers we have counts for

collaborators

24 papers

math.OC2025

Convergence of Momentum-Based Optimization Algorithms with Time-Varying Parameters

Mathukumalli Vidyasagar

In this paper, we present a unified algorithm for stochastic optimization that makes use of a "momentum" term; in other words, the stochastic gradient depends not only on the curre…

cs.LG2023

A Tutorial Introduction to Reinforcement Learning

Mathukumalli Vidyasagar

In this paper, we present a brief survey of Reinforcement Learning (RL), with particular emphasis on Stochastic Approximation (SA) as a unifying theme. The scope of the paper inclu…

math.OC2023

Convergence of the Stochastic Heavy Ball Method With Approximate Gradients and/or Block Updating

Uday Kiran Reddy Tadipatri, Mathukumalli Vidyasagar

In this paper, we establish the convergence of the stochastic Heavy Ball (SHB) algorithm under more general conditions than in the current literature. Specifically, (i) The stochas…

stat.ME2022★ 1 cited

Estimating large causal polytrees from small samples

Sourav Chatterjee, Mathukumalli Vidyasagar

We consider the problem of estimating a large causal polytree from a relatively small i.i.d. sample. This is motivated by the problem of determining causal structure when the numbe…

math.OC2022

Convergence of Batch Updating Methods with Approximate Gradients and/or Noisy Measurements: Theory and Computational Results

Tadipatri Uday Kiran Reddy, M. Vidyasagar

In this paper, we present a unified and general framework for analyzing the batch updating approach to nonlinear, high-dimensional optimization. The framework encompasses all the c…

stat.ML2022

Convergence of Stochastic Approximation via Martingale and Converse Lyapunov Methods

M. Vidyasagar

In this paper, we study the almost sure boundedness and the convergence of the stochastic approximation (SA) algorithm. At present, most available convergence proofs are based on t…

q-bio.PE2021★ 1 cited

SUTRA: A Novel Approach to Modelling Pandemics with Applications to COVID-19

Manindra Agrawal, Madhuri Kanitkar, Deepu Phillip +5

The Covid-19 pandemic has two key properties: (i) asymptomatic cases (both detected and undetected) that can result in new infections, and (ii) time-varying characteristics due to…

q-bio.PE2020★ 6 cited

Estimating Hidden Asymptomatics, Herd Immunity Threshold and Lockdown Effects using a COVID-19 Specific Model

Shaurya Kaushal, Abhineet Singh Rajput, Soumyadeep Bhattacharya +4

A quantitative COVID-19 model that incorporates hidden asymptomatic patients is developed, and an analytic solution in parametric form is given. The model incorporates the impact o…

stat.ML2019

New and Explicit Constructions of Unbalanced Ramanujan Bipartite Graphs

Shantanu Prasad Burnwal, Kaneenika Sinha, Mathukumalli Vidyasagar

The objectives of this article are three-fold. Firstly, we present for the first time explicit constructions of an infinite family of \textit{unbalanced} Ramanujan bigraphs. Second…

stat.ML2019

Deterministic Completion of Rectangular Matrices Using Asymmetric Ramanujan Graphs: Exact and Stable Recovery

Shantanu Prasad Burnwal, Mathukumalli Vidyasagar

In this paper we study the matrix completion problem: Suppose is unknown except for a known upper bound on its rank. By measuring a small n…

stat.ML2018

Compressed Sensing Using Binary Matrices of Nearly Optimal Dimensions

Mahsa Lotfi, Mathukumalli Vidyasagar

In this paper, we study the problem of compressed sensing using binary measurement matrices and -norm minimization (basis pursuit) as the recovery algorithm. We derive new…

stat.ML2017

An Approach to One-Bit Compressed Sensing Based on Probably Approximately Correct Learning Theory

Mehmet Eren Ahsen, Mathukumalli Vidyasagar

In this paper, the problem of one-bit compressed sensing (OBCS) is formulated as a problem in probably approximately correct (PAC) learning. It is shown that the Vapnik-Chervonenki…

eess.SY2017

CLOT Norm Minimization for Continuous Hands-off Control

Niharika Challapalli, Masaaki Nagahara, Mathukumalli Vidyasagar

In this paper, we consider hands-off control via minimization of the CLOT (Combined -One and Two) norm. The maximum hands-off control is the -optimal (or the sparsest) cont…

cs.IT2017

A Fast Noniterative Algorithm for Compressive Sensing Using Binary Measurement Matrices

Mahsa Lotfi, Mathukumalli Vidyasagar

In this paper we present a new algorithm for compressive sensing that makes use of binary measurement matrices and achieves exact recovery of ultra sparse vectors, in a single pass…

eess.SY2016

Continuous Hands-off Control by CLOT Norm Minimization

Niharika Challapalli, Masaaki Nagahara, Mathukumalli Vidyasagar

In this paper, we consider hands-off control via minimization of the CLOT (Combined L-One and Two) norm. The maximum hands-off control is the L0-optimal (or the sparsest) control a…

stat.ML2016

Tight Performance Bounds for Compressed Sensing With Conventional and Group Sparsity

Shashank Ranjan, Mathukumalli Vidyasagar

In this paper, we study the problem of recovering a group sparse vector from a small number of linear measurements. In the past the common approach has been to use various "group s…

stat.ML2015★ 1 cited

Error Bounds for Compressed Sensing Algorithms With Group Sparsity: A Unified Approach

M. Eren Ahsen, M. Vidyasagar

In compressed sensing, in order to recover a sparse or nearly sparse vector from possibly noisy measurements, the most popular approach is -norm minimization. Upper bounds…

stat.ML2014

Two New Approaches to Compressed Sensing Exhibiting Both Robust Sparse Recovery and the Grouping Effect

Mehmet Eren Ahsen, Niharika Challapalli, Mathukumalli Vidyasagar

In this paper we introduce a new optimization formulation for sparse regression and compressed sensing, called CLOT (Combined L-One and Two), wherein the regularizer is a convex co…

q-bio.QM2014★ 37 cited

Machine Learning Methods in the Computational Biology of Cancer

Mathukumalli Vidyasagar

The objectives of this "perspective" paper are to review some recent advances in sparse feature selection for regression and classification, as well as compressed sensing, and to d…

stat.ML2014

Near-Ideal Behavior of Compressed Sensing Algorithms

Mehmet Eren Ahsen, Mathukumalli Vidyasagar

In a recent paper, it is shown that the LASSO algorithm exhibits "near-ideal behavior," in the following sense: Suppose where satisfies the restricted isometry pro…

math.ST2013

An Elementary Derivation of the Large Deviation Rate Function for Finite State Markov Chains

Mathukumalli Vidyasagar

Large deviation theory is a branch of probability theory that is devoted to a study of the "rate" at which empirical estimates of various quantities converge to their true values.…

q-bio.GN2012★ 2 cited

Reverse Engineering Gene Interaction Networks Using the Phi-Mixing Coefficient

Nitin Kumar Singh, M. Eren Ahsen, Shiva Mankala +3

Constructing gene interaction networks (GINs) from high-throughput gene expression data is an important and challenging problem in systems biology. Existing algorithms produce netw…

stat.CO2012

Mixing Coefficients Between Discrete and Real Random Variables: Computation and Properties

Mehmet Eren Ahsen, Mathukumalli Vidyasagar

In this paper we study the problem of estimating the alpha-, beta- and phi-mixing coefficients between two random variables, that can either assume values in a finite set or the se…

eess.SY2011

A Metric Between Probability Distributions on Finite Sets of Different Cardinalities and Applications to Order Reduction

Mathukumalli Vidyasagar

With increasing use of digital control it is natural to view control inputs and outputs as stochastic processes assuming values over finite alphabets rather than in a Euclidean spa…