2 citations · 3 across the 6 of their papers we have counts for
6 papers
Enzyme kinetics: A note on negative reaction constants in Lineweaver-Burk plots
Sharmistha Dhatt, Kamal Bhattacharyya
Reaction constants in traditional Michaelis-Menten type enzyme kinetics are most often determined through a linear Lineweaver-Burk plot. While such a graphical plot is sometimes go…
How can we distinguish positive cooperativity from auto-catalysis in enzyme kinetics?
Sharmistha Dhatt, Kinshuk Banerjee, Kamal Bhattacharyya
Different graphical plots involving the catalytic rate with the (initial) substrate concentration exist in the enzyme kinetics literature to estimate the reaction constants. But, n…
Questioning the reliability of estimates of enzyme inhibitor constant: Case of competitive inhibition
Sharmistha Dhatt
Reliability of kinetic parameters are crucial in understanding enzyme kinetics within cellular system. The present study suggests a few cautions that need introspection for estimat…
Accurate estimates of asymptotic indices via fractional calculus
Sharmistha Dhatt, Kamal Bhattacharyya
We devise a three-parameter random search strategy to obtain accurate estimates of the large-coupling amplitude and exponent of an observable from its divergent Taylor expansion, k…
Enzyme Kinetics: A critique of the quasi-steady-state approximation
Kamal Bhattacharyya, Sharmistha Dhatt
The standard two-step model of homogeneous-catalyzed reactions had been theoretically analyzed at various levels of approximations from time to time. The primary aim was to check t…
Single-substrate Enzyme Kinetics: The Quasi-steady-state Approximation and Beyond
Sharmistha Dhatt, Kamal Bhattacharyya
We analyze the standard model of enzyme-catalyzed reactions at various substrate-enzyme ratios to identify the regions of validity of the quasi-steady-state approximation. Certain…