755 citations · 1.6k across the 34 of their papers we have counts for
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Recovering protein conformations from single-particle cryo-EM data via indirect shape matching gradient flows
Erik Jansson, Jonathan Krook, Ozan Öktem +1
Single-particle cryo-electron microscopy images a macromolecule as many noisy tomographic projections of its electrostatic potential. We reconstruct the protein backbone directly f…
Motion-Enabled Tomography of Gaussian-Mixture Particles under Unknown Rigid-Body Motion with Parabolic Trajectories
Daniel Burrows, Can Evren Yarman, Ozan Öktem
Reconstructing objects with unknown position and/or orientation arises in applications spanning geology to cryo-ET. When the relative motion between the object and the sensing appa…
Protein Graph Neural Networks for Heterogeneous Cryo-EM Reconstruction
Jonathan Krook, Axel Janson, Joakim Andén +2
We present a geometry-aware method for heterogeneous single-particle cryogenic electron microscopy (cryo-EM) reconstruction that predicts atomic backbone conformations. To incorpor…