67 citations · 198 across the 5 of their papers we have counts for
5 papers
Variable domain N-linked glycosylation and negative surface charge are key features of monoclonal ACPA: implications for B-cell selection
Katy A. Lloyd, Johanna Steen, Khaled Amara +15
Autoreactive B cells have a central role in the pathogenesis of rheumatoid arthritis (RA), and recent findings have proposed that anti-citrullinated protein autoantibodies (ACPA) m…
Autoreactivity to malondialdehyde-modifications in rheumatoid arthritis is linked to disease activity and synovial pathogenesis
Caroline Gronwall, Khaled Amara, Uta Hardt +12
Oxidation-associated malondialdehyde (MDA) modification of proteins can generate immunogenic neo-epitopes that are recognized by autoantibodies. In health, IgM antibodies to MDA-ad…
Isotopic Resonance Hypothesis: Experimental Verification by Escherichia coli Growth Measurements
Xueshu Xie, Roman A. Zubarev
Isotopic composition of reactants affects the rates of chemical and biochemical reactions. As a rule, enrichment of heavy stable isotopes leads to slower reactions. But the recent…
Expression proteomics reveals protein targets and highlights mechanisms of action of small molecule drugs
Alexey Chernobrovkin, Consuelo Marin Vicente, Neus Visa +1
Phenomenological screening of small molecule libraries for anticancer activity yields potentially interesting candidate molecules, with a bottleneck in the determination of drug ta…
Effects of low-level deuterium enrichment on bacterial growth
Xueshu Xie, Roman A. Zubarev
Using very precise (up to 0.05%) measurements of the growth parameters for bacteria E. coli grown on minimal media, we aimed to determine the lowest deuterium concentration at whic…