28 citations · 54 across the 9 of their papers we have counts for
9 papers
Thermodynamic limits on general far-from-equilibrium molecular templating networks
Benjamin Qureshi, Jenny M. Poulton, Thomas E. Ouldridge
Cells produce RNA and proteins via molecular templating networks. We show that information transmission in such networks is bounded by functions of a simple thermodynamic property…
Predicting a noisy signal: the costs and benefits of time averaging as a noise mitigation strategy
Jenny Poulton, Age Tjalma, Lotte Slim +1
One major challenge for living cells is the measurement and prediction of signals corrupted by noise. In general, cells need to make decisions based on their compressed representat…
Evolution with recombination as a Metropolis-Hastings sampling procedure
Jenny M. Poulton, Lee Altenberg, Chris Watkins
This work presents a population genetic model of evolution, which includes haploid selection, mutation, recombination, and drift. The mutation-selection equilibrium can be expresse…
A Universal Method for Analysing Copolymer Growth
Benjamin J. Qureshi, Jordan Juritz, Jenny M. Poulton +2
Polymers consisting of more than one type of monomer, known as copolymers, are vital to both living and synthetic systems. Copolymerisation has been studied theoretically in a numb…
Minimal mechanism for cyclic templating of length-controlled copolymers under isothermal conditions
Jordan Juritz, Jenny M Poulton, Thomas E Ouldridge
The production of sequence-specific copolymers using copolymer templates is fundamental to the synthesis of complex biological molecules and is a promising framework for the synthe…
The long and short of templated copying
Jenny Poulton
Templated copying is the central operation by which biology produces complex molecules. Cells copy sequence information from DNA to RNA and on into proteins, which are the molecule…
Edge-effects dominate copying thermodynamics for finite-length molecular oligomers
Jenny Marie Poulton, Thomas Edward Ouldridge
Living systems produce copies of information-carrying molecules such as DNA by assembling monomer units into finite-length oligomer (short polymer) copies. We explore the role of i…
Non-equilibrium correlations in minimal dynamical models of polymer copying
Jenny Poulton, Pieter Rein ten Wolde, Thomas E Ouldridge
Living systems produce "persistent" copies of information-carrying polymers, in which template and copy sequences remain correlated after physically decoupling. We identify a gener…
Dynamics influencing ordering of a s=3 Ising antiferromagnetic on a triangular lattice
Christopher Bentham, Stuart George, Jenny Poulton +1
Antiferromagnetically coupled Ising s =3 spins on a triangular lattice are very close to ordering at zero temperature. The low temperature behaviour of a triangular lattice with Is…