113 citations · 292 across the 31 of their papers we have counts for
8 papers · 1 filter
Dimensionality reduction of neuronal degeneracy reveals two interfering physiological mechanisms
Arthur Fyon, Alessio Franci, Pierre Sacré +1
Neuronal systems maintain stable functions despite large variability in their physiological components. Ion channel expression, in particular, is highly variable in neurons exhibit…
Cellular switches orchestrate rhythmic circuits
Guillaume Drion, Alessio Franci, Rodolphe Sepulchre
Small inhibitory neuronal circuits have long been identified as key neuronal motifs to generate and modulate the coexisting rhythms of various motor functions. Our paper highlights…
Robust and tunable bursting requires slow positive feedback
Alessio Franci, Guillaume Drion, Rodolphe Sepulchre
We highlight that the robustness and tunability of a bursting model critically relies on currents that provide slow positive feedback to the membrane potential. Such currents have…
Excitable behaviors
Rodolphe Sepulchre, Guillaume Drion, Alessio Franci
This chapter revisits the concept of excitability, a basic system property of neurons. The focus is on excitable systems regarded as behaviors rather than dynamical systems. By thi…
A positive feedback at the cellular level promotes robustness and modulation at the circuit level
Julie Dethier, Guillaume Drion, Alessio Franci +1
The paper highlights the role of a positive feedback gating mechanism at the cellular level in the robust- ness and modulation properties of rhythmic activities at the circuit leve…
Modulation of beta oscillations during movement initiation: modeling the ionic basis of a functional switch
Julie Dethier, Guillaume Drion, Alessio Franci +1
We use a computational model to propose a physiological mechanism by which transient control of beta oscillations in the indirect pathway of the basal ganglia is orchestrated at th…
Modulation and Robustness of Endogenous Neuronal Spiking
Guillaume Drion, Alessio Franci, Vincent Seutin +1
Neuronal spiking exhibits an exquisite combination of modulation and robustness properties, rarely matched in artificial systems. We exploit the particular interconnection structur…
A Balance Equation Determines a Switch in Neuronal Excitability
Alessio Franci, Guillaume Drion, Vincent Seutin +1
We use the qualitative insight of a planar neuronal phase portrait to detect an excitability switch in arbitrary conductance-based models from a simple mathematical condition. The…