37 citations · 50 across the 20 of their papers we have counts for
3 papers · 1 filter
A multi-arm multi-stage platform design that allows pre-planned addition of arms while still controlling the family-wise error
Peter Greenstreet, Thomas Jaki, Alun Bedding +2
There is growing interest in platform trials that allow for adding of new treatment arms as the trial progresses as well as being able to stop treatments part way through the trial…
A Comparison of Various Aggregation Functions in Multi-Criteria Decision Analysis for Drug Benefit-Risk Assessment
Tom Menzies, Gaelle Saint-Hilary, Pavel Mozgunov
Multi-criteria decision analysis (MCDA) is a quantitative approach to the drug benefit-risk assessment (BRA) which allows for consistent comparisons by summarising all benefits and…
A Comparison of Model-Free Phase I Dose Escalation Designs for Dual-Agent Combination Therapies
Helen Yvette Barnett, Matthew George, Donia Skanji +3
It is increasingly common for therapies in oncology to be given in combination. In some cases, patients can benefit from the interaction between two drugs, although often at the ri…