The Activation Entropy Change in Enzymatic Reaction Catalyzed by Isochorismate-Pyruvate Lyase of Pseudomonas Aeruginosa PchB

Liangxu Xie, Zhe-Ning Chen, Mingjun Yang

The elucidation of entropic contribution to enzyme catalysis has been debated over decades. The recent experimentally measured activation enthalpy and entropy, for chorismate rearr…