7 papers
Optimal Heat Storage Sizing for District Heating Networks to Maximize Electricity Revenue from Combined Heat and Power Units
Martin Sollich, Maarten Blommaert
Integrating heat storages in district heating networks (DHNs) supports managing dynamic characteristics such as heat-demand variations and changing energy prices, and the intermitt…
LinkML: An Open Data Modeling Framework
Sierra A. T. Moxon, Harold Solbrig, Nomi L. Harris +33
Scientific research relies on well-structured, standardized data; however, much of it is stored in formats such as free-text lab notebooks, non-standardized spreadsheets, or data r…
The Cell Ontology in the age of single-cell omics
Shawn Zheng Kai Tan, Aleix Puig-Barbe, Damien Goutte-Gattat +32
Single-cell omics technologies have transformed our understanding of cellular diversity by enabling high-resolution profiling of individual cells. However, the unprecedented scale…
Why we need all the organisms: an exploration of the Monarch knowledge graph to aid mechanism discovery
Katherina Cortes, Daniel Korn, Sarah Gehrke +12
Research done using model organisms has been fundamental to the biological understanding of human genes, diseases and phenotypes. Model organisms provide tractable systems for expe…
Koza and Koza-Hub for born-interoperable knowledge graph generation using KGX
Daniel R Korn, Patrick Golden, Aaron Odell +10
Knowledge graph construction has become an essential domain for the future of biomedical research. But current approaches demand a high amount of redundant labor. These redundancie…
A Dynamic Framework for Semantic Grouping of Common Data Elements (CDE) Using Embeddings and Clustering
Madan Krishnamurthy, Daniel Korn, Melissa A Haendel +2
This research aims to develop a dynamic and scalable framework to facilitate harmonization of Common Data Elements (CDEs) across heterogeneous biomedical datasets by addressing cha…