2 papers
physics.bio-ph2020
Atomistic simulations of the human proteasome inhibited by a covalent ligand
Michal H. Kolář, Lars V. Bock, Helmut Grubmüller
The proteasome is a large biomolecular complex responsible for protein degradation. It is under intense research due to its fundamental role in cellular homeostasis, and tremendous…
physics.bio-ph2017
Molecular Simulations of the Ribosome and Associated Translation Factors
Lars V. Bock, Michal H. Kolář, Helmut Grubmüller
The ribosome is a macromolecular complex which is responsible for protein synthesis in all living cells according to their transcribed genetic information. Using X-ray crystallogra…