activity
20172022
most citedRational design of complex phenotype via network models

15 citations · 16 across the 8 of their papers we have counts for

collaborators

9 papers

math.DS2022★ 1 cited

Computer assisted proofs for transverse collision and near collision orbits in the restricted three body problem

Maciej J. Capinski, Shane Kepley, Jason D. Mireles James

This paper considers two point boundary value problems for conservative systems defined in multiple coordinate systems, and develops a flexible a-posteriori framework for computer…

math.DS2022

Global analysis of regulatory network dynamics: equilibria and saddle-node bifurcations

Shane Kepley, Konstantin Mischaikow, Elena Queirolo

In this paper we describe a combined combinatorial/numerical approach to studying equilibria and bifurcations in network models arising in Systems Biology. ODE models of the dynami…

math.DS2021

Extending combinatorial regulatory network modeling to include activity control and decay modulation

Bree Cummins, Marcio Gameiro, Tomas Gedeon +3

Understanding how the structure of within-system interactions affects the dynamics of the system is important in many areas of science. We extend a network dynamics modeling platfo…

math.DS2020★ 15 cited

Rational design of complex phenotype via network models

Marcio Gameiro, Tomas Gedeon, Shane Kepley +1

We demonstrate a modeling and computational framework that allows for rapid screening of thousands of potential network designs for particular dynamic behavior. To illustrate this…

math.CO2020

Computing linear extensions for polynomial posets subject to algebraic constraints

Shane Kepley, Konstantin Mischaikow, Lun Zhang

In this paper we consider the classical problem of computing linear extensions of a given poset which is well known to be a difficult problem. However, in our setting the elements…

math.CA2019

A constructive proof of the Cauchy-Kovalevskaya theorem for ordinary differential equations

Shane Kepley, Tianhao Zhang

We give a constructive proof of the classical Cauchy-Kovalevskaya theorem in the ODE setting which provides a sufficient condition for an initial value problem to have a unique ana…

math.DS2018

Homoclinic dynamics in a restricted four body problem

Shane Kepley, J. D. Mireles James

We describe a method for computing an atlas for the stable or unstable manifold attached to an equilibrium point, and implement the method for the saddle-focus libration points of…

math.DS2017

Chaotic motions in the restricted four body problem via Devaney's saddle-focus homoclinic tangle theorem

Shane Kepley, J. D. Mireles James

We prove the existence of chaotic motions in a planar restricted four body problem, establishing that the system is not integrable. The idea of the proof is to verify the hypothese…

math.DS2017

Analytic continuation of local (un)stable manifolds with rigorous computer assisted error bounds

William D. Kalies, Shane Kepley, J. D. Mireles James

We develop a validated numerical procedure for continuation of local stable/unstable manifold patches attached to equilibrium solutions of ordinary differential equations. The proc…