221 citations · 493 across the 16 of their papers we have counts for
16 papers
Murine AI excels at cats and cheese: Structural differences between human and mouse neurons and their implementation in generative AIs
Rino Saiga, Kaede Shiga, Yo Maruta +19
Mouse and human brains have different functions that depend on their neuronal networks. In this study, we analyzed nanometer-scale three-dimensional structures of brain tissues of…
Structural aging of human neurons is the opposite of the changes in schizophrenia
Ryuta Mizutani, Rino Saiga, Yoshiro Yamamoto +17
Human mentality develops with age and is altered in psychiatric disorders, though their underlying mechanism is unknown. In this study, we analyzed nanometer-scale three-dimensiona…
Schizophrenia-mimicking layers outperform conventional neural network layers
Ryuta Mizutani, Senta Noguchi, Rino Saiga +4
We have reported nanometer-scale three-dimensional studies of brain networks of schizophrenia cases and found that their neurites are thin and tortuous compared to healthy controls…
Structural diverseness of neurons between brain areas and between cases
Ryuta Mizutani, Rino Saiga, Yoshiro Yamamoto +17
The cerebral cortex is composed of multiple cortical areas that exert a wide variety of brain functions. Although human brain neurons are genetically and areally mosaic, the three-…
Synchrotron radiation microtomography of brain hemisphere and spinal cord of a mouse model of multiple sclerosis revealed a correlation between capillary dilation and clinical score
Rino Saiga, Masato Hoshino, Akihisa Takeuchi +7
Multiple sclerosis is a neurological disorder in which the myelin sheaths of axons are damaged by the immune response. We report here a three-dimensional structural analysis of bra…
Three-dimensional alteration of neurites in schizophrenia
Ryuta Mizutani, Rino Saiga, Akihisa Takeuchi +16
This paper reports nano-CT analysis of brain tissues of schizophrenia and control cases. The analysis revealed that: (1) neuronal structures vary between individuals, (2) the mean…
Method for estimating modulation transfer function from sample images
Rino Saiga, Akihisa Takeuchi, Kentaro Uesugi +3
The modulation transfer function (MTF) represents the frequency domain response of imaging modalities. Here, we report a method for estimating the MTF from sample images. Test imag…
Estimating the resolution of real images
Ryuta Mizutani, Rino Saiga, Susumu Takekoshi +9
Image resolvability is the primary concern in imaging. This paper reports an estimation of the full width at half maximum of the point spread function from a Fourier domain plot of…
Three-dimensional X-ray visualization of axonal tracts in mouse brain hemisphere
Ryuta Mizutani, Rino Saiga, Masato Ohtsuka +4
Neurons transmit active potentials through axons, which are essential for the brain to function. In this study, the axonal networks of the murine brain were visualized with X-ray t…
Three-dimensional microtomographic imaging of human brain cortex
Ryuta Mizutani, Akihisa Takeuchi, Kentaro Uesugi +4
This paper describes an x-ray microtomographic technique for imaging the three-dimensional structure of the human cerebral cortex. Neurons in the brain constitute a neural circuit…
X-ray microtomographic visualization of Escherichia coli by metalloprotein overexpression
Ryuta Mizutani, Keisuke Taguchi, Masato Ohtsuka +4
This paper reports X-ray microtomographic visualization of the microorganism Escherichia coli overexpressing a metalloprotein ferritin. The three-dimensional distribution of linear…
Submicrometer tomographic resolution examined using a micro-fabricated test object
Ryuta Mizutani, Akihisa Takeuchi, R. Yoshiyuki Osamura +3
To estimate the spatial resolution of microtomographs, a test object on the submicrometer scale was prepared by focused ion beam milling and subjected to microtomographic analysis.…
Estimation of presampling modulation transfer function in synchrotron radiation microtomography
Ryuta Mizutani, Keisuke Taguchi, Akihisa Takeuchi +2
The spatial resolution achieved by recent synchrotron radiation microtomographs should be estimated from the modulation transfer function (MTF) on the micrometer scale. Step respon…
A method for estimating spatial resolution of real image in the Fourier domain
Ryuta Mizutani, Rino Saiga, Susumu Takekoshi +9
Spatial resolution is a fundamental parameter in structural sciences. In crystallography, the resolution is determined from the detection limit of high-angle diffraction in recipro…
X-ray microtomography in biology
Ryuta Mizutani, Yoshio Suzuki
Progress in high-resolution x-ray microtomography has provided us with a practical approach to determining three-dimensional (3D) structures of opaque samples at micrometer to subm…
Three-dimensional network of Drosophila brain hemisphere
Ryuta Mizutani, Rino Saiga, Akihisa Takeuchi +2
The first step to understanding brain function is to determine the brain's network structure. We report a three-dimensional analysis of the brain network of the fruit fly Drosophil…