2 papers
q-bio.PE2017
The standard genetic code facilitates exploration of the space of functional nucleotide sequences
Shubham Tripathi, Michael W. Deem
The standard genetic code is well known to be optimized for minimizing the phenotypic effects of single nucleotide substitutions, a property that was likely selected for during the…
q-bio.MN2017
Analysis of hierarchical organization in gene expression networks reveals underlying principles of collective tumor cell dissemination and metastatic aggressiveness of inflammatory breast cancer
Shubham Tripathi, Mohit Kumar Jolly, Wendy A. Woodward +2
Clusters of circulating tumor cells (CTCs), although rare, may account for more than 95% of metastases. Inflammatory breast cancer (IBC) is a highly aggressive subtype that chiefly…