5 citations · 12 across the 5 of their papers we have counts for
4 papers · 1 filter
Vital rates from the action of mutation accumulation
Kenneth W. Wachter, David R. Steinsaltz, Steven N. Evans
New models for evolutionary processes of mutation accumulation allow hypotheses about the age-specificity of mutational effects to be translated into predictions of heterogeneous p…
The Age-Specific Force of Natural Selection and Walls of Death
Kenneth W. Wachter, Steven N. Evans, David R. Steinsaltz
W. D. Hamilton's celebrated formula for the age-specific force of natural selection furnishes predictions for senescent mortality due to mutation accumulation, at the price of reli…
A mutation-selection model for general genotypes with recombination
Steven N. Evans, David Steinsaltz, Kenneth W. Wachter
We investigate a continuous time, probability measure-valued dynamical system that describes the process of mutation-selection balance in a context where the population is infinite…
A generalized model of mutation-selection balance with applications to aging
David Steinsaltz, Steven N. Evans, Kenneth W. Wachter
A probability model is presented for the dynamics of mutation-selection balance in a haploid infinite-population infinite-sites setting sufficiently general to cover mutation-drive…