activity
20172026
most citedContinuous State-Space Models for Optimal Sepsis Treatment - a Deep Reinforcement Learning Approach

102 citations · 364 across the 12 of their papers we have counts for

collaborators

12 papers

cs.LG2026

Kernel weighted importance sampling for off-policy evaluation in contextual bandits

Joshua Spear, Matthieu Komorowski, Rebecca Pope +1

This article presents a novel estimator for performing off-policy evaluation using only offline data for contextual bandits. The proposed estimator, Kernel-WIS is demonstrated to b…

cs.AI2021★ 2 cited

Enabling risk-aware Reinforcement Learning for medical interventions through uncertainty decomposition

Paul Festor, Giulia Luise, Matthieu Komorowski +1

Reinforcement Learning (RL) is emerging as tool for tackling complex control and decision-making problems. However, in high-risk environments such as healthcare, manufacturing, aut…

cs.AI2019★ 9 cited

Optimizing Sequential Medical Treatments with Auto-Encoding Heuristic Search in POMDPs

Luchen Li, Matthieu Komorowski, Aldo A. Faisal

Health-related data is noisy and stochastic in implying the true physiological states of patients, limiting information contained in single-moment observations for sequential clini…

cs.AI2019★ 2 cited

Understanding the Artificial Intelligence Clinician and optimal treatment strategies for sepsis in intensive care

Matthieu Komorowski, Leo A. Celi, Omar Badawi +2

In this document, we explore in more detail our published work (Komorowski, Celi, Badawi, Gordon, & Faisal, 2018) for the benefit of the AI in Healthcare research community. In the…

cs.LG2019★ 45 cited

Improving Sepsis Treatment Strategies by Combining Deep and Kernel-Based Reinforcement Learning

Xuefeng Peng, Yi Ding, David Wihl +6

Sepsis is the leading cause of mortality in the ICU. It is challenging to manage because individual patients respond differently to treatment. Thus, tailoring treatment to the indi…

cs.LG2018★ 27 cited

Model-Based Reinforcement Learning for Sepsis Treatment

Aniruddh Raghu, Matthieu Komorowski, Sumeetpal Singh

Sepsis is a dangerous condition that is a leading cause of patient mortality. Treating sepsis is highly challenging, because individual patients respond very differently to medical…