Assessing the Impact of Covariate Distribution and Positivity Violation on Weighting-Based Indirect Comparisons: a Simulation Study

Arnaud Serret-Larmande, Jérôme Lambert, Stéphane Gaudry +1

Population-Adjusted Indirect Comparisons (PAICs) are used to estimate treatment effects when direct comparisons are infeasible and individual patient data (IPD) are only available…