activity
20162025
most citedA simple normative network approximates local non-Hebbian learning in the cortex

4 citations · 13 across the 20 of their papers we have counts for

collaborators

23 papers

q-bio.NC2025

Modeling Neural Activity with Conditionally Linear Dynamical Systems

Victor Geadah, Amin Nejatbakhsh, David Lipshutz +2

Neural population activity exhibits complex, nonlinear dynamics, varying in time, over trials, and across experimental conditions. Here, we develop Conditionally Linear Dynamical S…

q-bio.NC2024★ 1 cited

Comparing noisy neural population dynamics using optimal transport distances

Amin Nejatbakhsh, Victor Geadah, Alex H. Williams +1

Biological and artificial neural systems form high-dimensional neural representations that underpin their computational capabilities. Methods for quantifying geometric similarity i…

stat.ML2024★ 2 cited

What Representational Similarity Measures Imply about Decodable Information

Sarah E. Harvey, David Lipshutz, Alex H. Williams

Neural responses encode information that is useful for a variety of downstream tasks. A common approach to understand these systems is to build regression models or ``decoders'' th…

q-bio.NC2024

Discriminating image representations with principal distortions

Jenelle Feather, David Lipshutz, Sarah E. Harvey +2

Image representations (artificial or biological) are often compared in terms of their global geometric structure; however, representations with similar global structure can have st…

q-bio.NC2024

Shaping the distribution of neural responses with interneurons in a recurrent circuit model

David Lipshutz, Eero P. Simoncelli

Efficient coding theory posits that sensory circuits transform natural signals into neural representations that maximize information transmission subject to resource constraints. L…

q-bio.NC2024

Neuronal Temporal Filters as Normal Mode Extractors

Siavash Golkar, Jules Berman, David Lipshutz +3

To generate actions in the face of physiological delays, the brain must predict the future. Here we explore how prediction may lie at the core of brain function by considering a ne…

q-bio.NC2023

Adaptive whitening with fast gain modulation and slow synaptic plasticity

Lyndon R. Duong, Eero P. Simoncelli, Dmitri B. Chklovskii +1

Neurons in early sensory areas rapidly adapt to changing sensory statistics, both by normalizing the variance of their individual responses and by reducing correlations between the…

q-bio.NC2023

Normative framework for deriving neural networks with multi-compartmental neurons and non-Hebbian plasticity

David Lipshutz, Yanis Bahroun, Siavash Golkar +2

An established normative approach for understanding the algorithmic basis of neural computation is to derive online algorithms from principled computational objectives and evaluate…

q-bio.NC2023★ 1 cited

Adaptive whitening in neural populations with gain-modulating interneurons

Lyndon R. Duong, David Lipshutz, David J. Heeger +2

Statistical whitening transformations play a fundamental role in many computational systems, and may also play an important role in biological sensory systems. Existing neural circ…

stat.ML2022★ 1 cited

An online algorithm for contrastive Principal Component Analysis

Siavash Golkar, David Lipshutz, Tiberiu Tesileanu +1

Finding informative low-dimensional representations that can be computed efficiently in large datasets is an important problem in data analysis. Recently, contrastive Principal Com…

q-bio.NC2022

Interneurons accelerate learning dynamics in recurrent neural networks for statistical adaptation

David Lipshutz, Cengiz Pehlevan, Dmitri B. Chklovskii

Early sensory systems in the brain rapidly adapt to fluctuating input statistics, which requires recurrent communication between neurons. Mechanistically, such recurrent communicat…

cs.NE2020★ 3 cited

A biologically plausible neural network for local supervision in cortical microcircuits

Siavash Golkar, David Lipshutz, Yanis Bahroun +2

The backpropagation algorithm is an invaluable tool for training artificial neural networks; however, because of a weight sharing requirement, it does not provide a plausible model…

q-bio.NC2020★ 4 cited

A simple normative network approximates local non-Hebbian learning in the cortex

Siavash Golkar, David Lipshutz, Yanis Bahroun +2

To guide behavior, the brain extracts relevant features from high-dimensional data streamed by sensory organs. Neuroscience experiments demonstrate that the processing of sensory i…

q-bio.NC2020★ 1 cited

A biologically plausible neural network for Slow Feature Analysis

David Lipshutz, Charlie Windolf, Siavash Golkar +1

Learning latent features from time series data is an important problem in both machine learning and brain function. One approach, called Slow Feature Analysis (SFA), leverages the…

eess.SP2020

Biologically plausible single-layer networks for nonnegative independent component analysis

David Lipshutz, Cengiz Pehlevan, Dmitri B. Chklovskii

An important problem in neuroscience is to understand how brains extract relevant signals from mixtures of unknown sources, i.e., perform blind source separation. To model how the…

q-bio.NC2020

A biologically plausible neural network for multi-channel Canonical Correlation Analysis

David Lipshutz, Yanis Bahroun, Siavash Golkar +2

Cortical pyramidal neurons receive inputs from multiple distinct neural populations and integrate these inputs in separate dendritic compartments. We explore the possibility that c…

math.PR2020

Customer-server population dynamics in heavy traffic

Rami Atar, Prasenjit Karmakar, David Lipshutz

We study a many-server queueing model with server vacations, where the population size dynamics of servers and customers are coupled: a server may leave for vacation only when no c…

math.PR2019

Sensitivity analysis for the stationary distribution of reflected Brownian motion in a convex polyhedral cone

David Lipshutz, Kavita Ramanan

Reflected Brownian motion (RBM) in a convex polyhedral cone arises in a variety of applications ranging from the theory of stochastic networks to math finance, and under general st…

math.DS2018

Stability of synchronous slowly oscillating periodic solutions for systems of delay differential equations with coupled nonlinearity

David Lipshutz, Robert J. Lipshutz

We study stability of so-called synchronous slowly oscillating periodic solutions (SOPSs) for a system of identical delay differential equations (DDEs) with linear decay and nonlin…

math.PR2017

A Monte Carlo method for estimating sensitivities of reflected diffusions in convex polyhedral domains

David Lipshutz, Kavita Ramanan

In this work we develop an effective Monte Carlo method for estimating sensitivities, or gradients of expectations of sufficiently smooth functionals, of a reflected diffusion in a…

math.PR2017

Exit time asymptotics for small noise stochastic delay differential equations

David Lipshutz

Dynamical system models with delayed dynamics and small noise arise in a variety of applications in science and engineering. In many applications, stable equilibrium or periodic be…

math.PR2017

Pathwise differentiability of reflected diffusions in convex polyhedral domains

David Lipshutz, Kavita Ramanan

Reflected diffusions in convex polyhedral domains arise in a variety of applications, including interacting particle systems, queueing networks, biochemical reaction networks and m…

math.PR2016

On directional derivatives of Skorokhod maps in convex polyhedral domains

David Lipshutz, Kavita Ramanan

The study of both sensitivity analysis and differentiability of the stochastic flow of a reflected process in a convex polyhedral domain is challenging because the dynamics are dis…