activity
20172023
most citedAccelerating Antimicrobial Discovery with Controllable Deep Generative Models and Molecular Dynamics

429 citations · 678 across the 10 of their papers we have counts for

collaborators

11 papers

cs.CL2023

Causal ATE Mitigates Unintended Bias in Controlled Text Generation

Rahul Madhavan, Kahini Wadhawan

We study attribute control in language models through the method of Causal Average Treatment Effect (Causal ATE). Existing methods for the attribute control task in Language Models…

cs.CL2023

CFL: Causally Fair Language Models Through Token-level Attribute Controlled Generation

Rahul Madhavan, Rishabh Garg, Kahini Wadhawan +1

We propose a method to control the attributes of Language Models (LMs) for the text generation task using Causal Average Treatment Effect (ATE) scores and counterfactual augmentati…

cs.LG2022★ 1 cited

Attribute Graphs Underlying Molecular Generative Models: Path to Learning with Limited Data

Samuel C. Hoffman, Payel Das, Karthikeyan Shanmugam +2

Training generative models that capture rich semantics of the data and interpreting the latent representations encoded by such models are very important problems in un-/self-superv…

q-bio.QM2021★ 6 cited

Towards Interpreting Zoonotic Potential of Betacoronavirus Sequences With Attention

Kahini Wadhawan, Payel Das, Barbara A. Han +4

Current methods for viral discovery target evolutionarily conserved proteins that accurately identify virus families but remain unable to distinguish the zoonotic potential of newl…

cs.LG2020★ 75 cited

Optimizing Molecules using Efficient Queries from Property Evaluations

Samuel Hoffman, Vijil Chenthamarakshan, Kahini Wadhawan +2

Machine learning based methods have shown potential for optimizing existing molecules with more desirable properties, a critical step towards accelerating new chemical discovery. H…

cs.CL2020

Effects of Naturalistic Variation in Goal-Oriented Dialog

Jatin Ganhotra, Robert Moore, Sachindra Joshi +1

Existing benchmarks used to evaluate the performance of end-to-end neural dialog systems lack a key component: natural variation present in human conversations. Most datasets are c…

cs.LG2020★ 429 cited

Accelerating Antimicrobial Discovery with Controllable Deep Generative Models and Molecular Dynamics

Payel Das, Tom Sercu, Kahini Wadhawan +12

De novo therapeutic design is challenged by a vast chemical repertoire and multiple constraints, e.g., high broad-spectrum potency and low toxicity. We propose CLaSS (Controlled La…

cs.LG2018★ 115 cited

Co-regularized Alignment for Unsupervised Domain Adaptation

Abhishek Kumar, Prasanna Sattigeri, Kahini Wadhawan +4

Deep neural networks, trained with large amount of labeled data, can fail to generalize well when tested with examples from a \emph{target domain} whose distribution differs from t…

q-bio.QM2018★ 18 cited

PepCVAE: Semi-Supervised Targeted Design of Antimicrobial Peptide Sequences

Payel Das, Kahini Wadhawan, Oscar Chang +6

Given the emerging global threat of antimicrobial resistance, new methods for next-generation antimicrobial design are urgently needed. We report a peptide generation framework Pep…

cs.CL2017★ 10 cited

Improved Neural Text Attribute Transfer with Non-parallel Data

Igor Melnyk, Cicero Nogueira dos Santos, Kahini Wadhawan +2

Text attribute transfer using non-parallel data requires methods that can perform disentanglement of content and linguistic attributes. In this work, we propose multiple improvemen…

cs.LG2017★ 24 cited

Learning Loss Functions for Semi-supervised Learning via Discriminative Adversarial Networks

Cicero Nogueira dos Santos, Kahini Wadhawan, Bowen Zhou

We propose discriminative adversarial networks (DAN) for semi-supervised learning and loss function learning. Our DAN approach builds upon generative adversarial networks (GANs) an…