69 citations · 132 across the 7 of their papers we have counts for
7 papers
Yielding behaviour of active particles in bulk and in confinement
Yagyik Goswami, G. V. Shivashankar, Srikanth Sastry
The investigation of collective behaviour in dense assemblies of self-propelled active particles has been motivated by a wide range of biological phenomena. Of particular interest…
Chromatin remodeling due to transient-link-and-pass activity enhances subnuclear dynamics
Rakesh Das, Takahiro Sakaue, G. V. Shivashankar +2
Spatiotemporal coordination of chromatin and subnuclear compartments is crucial for cells. Numerous enzymes act inside nucleus\textemdash some of those transiently link and pass tw…
Causal Network Models of SARS-CoV-2 Expression and Aging to Identify Candidates for Drug Repurposing
Anastasiya Belyaeva, Louis Cammarata, Adityanarayanan Radhakrishnan +4
Given the severity of the SARS-CoV-2 pandemic, a major challenge is to rapidly repurpose existing approved drugs for clinical interventions. While a number of data-driven and exper…
Active nano-mechanical stimulation of single cells for mechanobiology
M. Monticelli, D. S. Jokhun, D. Petti +2
In-vivo, cells are frequently exposed to multiple mechanical stimuli arising from the extracellular microenvironment, with deep impact on many biological functions. On the other ha…
Soft inclusion in a confined fluctuating active gel
Amit Singh Vishen, Jean-Francois Rupprecht, G. V. Shivashankar +2
We study stochastic dynamics of a point and extended inclusion within a one dimensional confined active viscoelastic gel. We show that the dynamics of a point inclusion can be desc…
Maximal fluctuations of confined actomyosin gels: dynamics of the cell nucleus
Jean-Francois Rupprecht, Amit Singh Vishen, G. V. Shivashankar +2
We investigate the effect of stress fluctuations on the stochastic dynamics of an inclusion embedded in a viscous gel. We show that, in non-equilibrium systems, stress fluctuations…
Actomyosin contractility rotates the cell nucleus
Abhishek Kumar, Ananyo Maitra, Madhuresh Sumit +2
The nucleus of the eukaryotic cell functions amidst active cytoskeletal filaments, but its response to the stresses carried by these filaments is largely unexplored. We report here…