140 citations · 232 across the 8 of their papers we have counts for
8 papers
Using the force landscape of an active solid to predict plastic deformation
Tyler Hain, Edan Lerner, M. Lisa Manning
Non-active disordered solids feature quasilocalized excitations that control plasticity, similar to crystal lattice defects, and these excitations can be identified via harmonic or…
Rigidity and mechanical response in biological structures
Kelly Aspinwall, Tyler Hain, M. Lisa Manning
Rigidity is an emergent property of materials - it is not a feature of individual components that comprise the structure, but instead arises from interactions between many constitu…
Optimizing properties on the critical rigidity manifold of underconstrained central-force networks
Tyler Hain, Chris Santangelo, M. Lisa Manning
Our goal is to develop a design framework for multifunctional mechanical metamaterials that can tune their rigidity while optimizing other desired properties. Towards this goal, we…
Scaling regimes and fluctuations of observables in computer glasses approaching the unjamming transition
Julia A. Giannini, Edan Lerner, Francesco Zamponi +1
Under decompression, disordered solids undergo an unjamming transition where they become under-coordinated and lose their structural rigidity. The mechanical and vibrational proper…
A direct link between active matter and sheared granular systems
Peter K. Morse, Sudeshna Roy, Elisabeth Agoritsas +3
The similarity in mechanical properties of dense active matter and sheared amorphous solids has been noted in recent years without a rigorous examination of the underlying mechanis…
Tissue flow induces cell shape changes during organogenesis
Gonca Erdemci-Tandogan, Madeline J. Clark, Jeffrey D. Amack +1
In embryonic development, programmed cell shape changes are essential for building functional organs, but in many cases the mechanisms that precisely regulate these changes remain…
Identifying the mechanism for superdiffusivity in mouse fibroblast motility
G Passucci, ME Brasch, JH Henderson +2
We seek to characterize the motility of mouse fibroblasts on 2D substrates. Utilizing automated tracking techniques, we find that cell trajectories are super-diffusive, where displ…
Correlating Cell Shape and Cellular Stress in Motile Confluent Tissues
Xingbo Yang, Dapeng Bi, Michael Czajkowski +3
Collective cell migration is a highly regulated process involved in wound healing, cancer metastasis and morphogenesis. Mechanical interactions among cells provide an important reg…