3 papers
stat.ME2025
Cure Rate Joint Model for Time-to-Event Data and Longitudinal Tumor Burden with Potential Change Points
Yixiang Qu, Ethan M. Alt, Weibin Zhong +3
In non-small cell lung cancer (NSCLC) clinical trials, tumor burden (TB) is a key longitudinal biomarker for assessing treatment effects. Typically, standard-of-care (SOC) therapie…
stat.ME2025
hdbayes: An R Package for Bayesian Analysis of Generalized Linear Models Using Historical Data
Ethan M. Alt, Xinxin Chen, Luiz M. Carvalho +1
There has been increased interest in the use of historical data to formulate informative priors in regression models. While many such priors for incorporating historical data have…
stat.ME2025
Improved computational efficiency and stability when imputing censored covariates: Analytic and numerical approaches
Sarah C. Lotspeich, Ethan M. Alt
Imputation is a popular approach to handling censored, missing, and error-prone covariates -- all coarsened data types for which the true values are unknown. However, there are nua…