55 citations · 158 across the 6 of their papers we have counts for
6 papers
Amino Acids Stabilizing Effect on Protein and Colloidal Dispersions
Ting Mao, Xufeng Xu, Pamina M. Winkler +7
Despite being used for decades as stabilizers, amino acids (AAs) remain mysterious components of many medical and biological formulations. Hypotheses on their role vary ranging fro…
Modulating weak protein-protein cross-interactions by addition of free amino acids at millimolar concentrations
Pamina M. Winkler, Cécilia Siri, Johann Buczkowski +4
In this paper, we quantify weak protein protein interactions in solution using Cross-Interaction Chromatography (CIC) and Surface Plasmon Resonance (SPR) and demonstrate that they…
Multiplexed plasmonic nanoantennas for high throughput single molecule nanoscale dynamics in living cells
Pamina M. Winkler, Thomas S. van Zanten, Satyajit Mayor +1
Single molecule detection has revolutionised the fields of chemistry and biology by offering powerful ways to study individual molecules under different scenarios. Nanophotonic str…
Optical Antenna-based Fluorescence Correlation Spectroscopy to Probe the Nanoscale Dynamics of Biological Membranes
Pamina M. Winkler, Raju Regmi, Valentin Flauraud +4
The plasma membrane of living cells is compartmentalized at multiple spatial scales ranging from the nano- to the meso-scale. This non-random organization is crucial for a large nu…
Transient Nanoscopic Phase Separation in Biological Lipid Membranes Resolved by Planar Plasmonic Antennas
Pamina M. Winkler, Raju Regmi, Valentin Flauraud +4
Nanoscale membrane assemblies of sphingolipids, cholesterol, and certain proteins, also known as lipid rafts, play a crucial role in facilitating a broad range of important cell fu…
Planar Optical Nanoantennas Resolve Cholesterol-Dependent Nanoscale Heterogeneities in the Plasma Membrane of Living Cells
Raju Regmi, Pamina M. Winkler, Valentin Flauraud +6
Optical nanoantennas can efficiently confine light into nanoscopic hotspots, enabling single-molecule detection sensitivity at biological relevant conditions. This innovative appro…