9 citations · 13 across the 4 of their papers we have counts for
4 papers
Invariant non-equilibrium dynamics of transcriptional regulation optimize information flow
Benjamin Zoller, Alexis Bénichou, Thomas Gregor +1
Eukaryotic gene regulation is based on stochastic yet controlled promoter switching, during which genes transition between transcriptionally active and inactive states. Despite the…
Gene activity fully predicts transcriptional bursting dynamics
Po-Ta Chen, Michal Levo, Benjamin Zoller +1
Transcription commonly occurs in bursts, with alternating productive (ON) and quiescent (OFF) periods, governing mRNA production rates. Yet, how transcription is regulated through…
Eukaryotic gene regulation at equilibrium, or non?
Benjamin Zoller, Thomas Gregor, Gašper Tkačik
Models of transcriptional regulation that assume equilibrium binding of transcription factors have been very successful at predicting gene expression from sequence in bacteria. How…
Diverse spatial expression patterns emerge from common transcription bursting kinetics
Benjamin Zoller, Shawn C. Little, Thomas Gregor
In early development, regulation of transcription results in precisely positioned and highly reproducible expression patterns that specify cellular identities. How transcription, a…