166 citations · 223 across the 5 of their papers we have counts for
5 papers
Modeling cell size regulation: From single-cell level statistics to molecular mechanisms and population level effects
Po-Yi Ho, Jie Lin, Ariel Amir
Most microorganisms regulate their cell size. We review here some of the mathematical formulations of the problem of cell size regulation. We focus on coarse-grained stochastic mod…
Details Matter: noise and model structure set the relationship between cell size and cell cycle timing
Felix Barber, Po-Yi Ho, Andrew W. Murray +1
Organisms across all domains of life regulate the size of their cells. However, the means by which this is done is poorly understood. We study two abstracted "molecular" models for…
Interrogating the Escherichia coli cell cycle by cell dimension perturbations
Hai Zheng, Po-Yi Ho, Meiling Jiang +7
Bacteria tightly regulate and coordinate the various events in their cell cycles to duplicate themselves accurately and to control their cell sizes. Growth of Escherichia coli, in…
Simultaneous regulation of cell size and chromosome replication in bacteria
Po-Yi Ho, Ariel Amir
Bacteria are able to maintain a narrow distribution of cell sizes by regulating the timing of cell divisions. In rich nutrient conditions, cells divide much faster than their chrom…
Calibrated Langevin dynamics simulations of intrinsically disordered proteins
W. Wendell Smith, Po-Yi Ho, Corey S. O'Hern
We perform extensive coarse-grained (CG) Langevin dynamics simulations of intrinsically disordered proteins (IDPs), which possess fluctuating conformational statistics between that…