49 citations · 132 across the 7 of their papers we have counts for
3 papers · 1 filter
Contrastive losses as generalized models of global epistasis
David H. Brookes, Jakub Otwinowski, Sam Sinai
Fitness functions map large combinatorial spaces of biological sequences to properties of interest. Inferring these multimodal functions from experimental data is a central task in…
Turbulent coherent structures and early life below the Kolmogorov scale
Madison S. Krieger, Sam Sinai, Martin A. Nowak
A great number of biological organisms live in aqueous environments. Major evolutionary transitions, including the emergence of life itself, likely occurred in such environments. W…
Primordial Sex Facilitates the Emergence of Evolution
Sam Sinai, Jason Olejarz, Iulia A. Neagu +1
Compartments are ubiquitous throughout biology, yet their importance stretches back to the origin of cells. In the context of origin of life, we assume that a protocell, a compartm…