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20182026
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math.OC2026

Optimal control of a tumor growth model with hyperbolic relaxation of the chemical potential

Pierluigi Colli, Elisabetta Rocca, Jürgen Sprekels

In this paper, we study the optimal control of a phase field model for a tumor growth model of Cahn--Hilliard type in which the often assumed parabolic relaxation of the chemical p…

math.OC2026

Optimal velocity control of a Brinkman-Cahn-Hilliard system with curvature effects

Pierluigi Colli, Gianni Gilardi, Andrea Signori +1

We address an optimal control problem governed by a system coupling a Brinkman-type momentum equation for the velocity field with a sixth-order Cahn-Hilliard equation for the phase…

math.OC2024

Second-order optimality conditions for the sparse optimal control of nonviscous Cahn-Hilliard systems

Pierluigi Colli, Jürgen Sprekels

In this paper we study the optimal control of an initial-boundary value problem for the classical nonviscous Cahn-Hilliard system with zero Neumann boundary conditions. Phase field…

math.OC2024

Optimality conditions for sparse optimal control of viscous Cahn-Hilliard systems with logarithmic potential

Pierluigi Colli, Jürgen Sprekels, Fredi Tröltzsch

In this paper we study the optimal control of a parabolic initial-boundary value problem of viscous Cahn-Hilliard type with zero Neumann boundary conditions. Phase field systems of…

math.OC2023

Nutrient control for a viscous Cahn-Hilliard-Keller-Segel model

Gianni Gilardi, Andrea Signori, Jürgen Sprekels

In this paper, we address a distributed control problem for a system of partial differential equations describing the evolution of a tumor that takes the biological mechanism of ch…

math.OC2023

Second-order sufficient conditions in the sparse optimal control of a phase field tumor growth model with logarithmic potential

Jürgen Sprekels, Fredi Tröltzsch

This paper treats a distributed optimal control problem for a tumor growth model of viscous Cahn--Hilliard type. The evolution of the tumor fraction is governed by a thermodynamic…