3 papers
q-bio.MN2025
Maximum likelihood estimation of log-affine models using detailed-balanced reaction networks
Oskar Henriksson, Carlos Améndola, Jose Israel Rodriguez +1
A fundamental question in the field of molecular computation is what computational tasks a biochemical system can carry out. In this work, we focus on the problem of finding the ma…
math.DS2024
Generalized Lotka-Volterra Systems and Complex Balanced Polyexponential Systems
Diego Rojas La Luz, Gheorghe Craciun, Polly Y. Yu
We study the global stability of generalized Lotka-Volterra systems with generalized polynomial right-hand side, without restrictions on the number of variables or the polynomial d…
q-bio.MN2024
A necessary condition for non-monotonic dose response, with an application to a kinetic proofreading model -- Extended version
Polly Y. Yu, Eduardo D. Sontag
Steady state nonmonotonic ("biphasic") dose responses are often observed in experimental biology, which raises the control-theoretic question of identifying which possible mechanis…