activity
20172025
most citedMitosis domain generalization in histopathology images -- The MIDOG challenge

162 citations · 195 across the 11 of their papers we have counts for

collaborators

13 papers

eess.IV2025

Sequential Hard Mining: a data-centric approach for Mitosis Detection

Maxime W. Lafarge, Viktor H. Koelzer

With a continuously growing availability of annotated datasets of mitotic figures in histology images, finding the best way to optimally use with this unprecedented amount of data…

cs.CV2023★ 2 cited

Domain generalization across tumor types, laboratories, and species -- insights from the 2022 edition of the Mitosis Domain Generalization Challenge

Marc Aubreville, Nikolas Stathonikos, Taryn A. Donovan +27

Recognition of mitotic figures in histologic tumor specimens is highly relevant to patient outcome assessment. This task is challenging for algorithms and human experts alike, with…

cs.LG2023★ 1 cited

CohortFinder: an open-source tool for data-driven partitioning of biomedical image cohorts to yield robust machine learning models

Fan Fan, Georgia Martinez, Thomas Desilvio +10

Batch effects (BEs) refer to systematic technical differences in data collection unrelated to biological variations whose noise is shown to negatively impact machine learning (ML)…

eess.IV2023

Multi-task learning for tissue segmentation and tumor detection in colorectal cancer histology slides

Lydia A. Schoenpflug, Maxime W. Lafarge, Anja L. Frei +1

Automating tissue segmentation and tumor detection in histopathology images of colorectal cancer (CRC) is an enabler for faster diagnostic pathology workflows. At the same time it…

eess.IV2023

Fine-Grained Hard Negative Mining: Generalizing Mitosis Detection with a Fifth of the MIDOG 2022 Dataset

Maxime W. Lafarge, Viktor H. Koelzer

Making histopathology image classifiers robust to a wide range of real-world variability is a challenging task. Here, we describe a candidate deep learning solution for the Mitosis…

eess.IV2022★ 162 cited

Mitosis domain generalization in histopathology images -- The MIDOG challenge

Marc Aubreville, Nikolas Stathonikos, Christof A. Bertram +32

The density of mitotic figures within tumor tissue is known to be highly correlated with tumor proliferation and thus is an important marker in tumor grading. Recognition of mitoti…

cs.LG2022★ 1 cited

Towards IID representation learning and its application on biomedical data

Jiqing Wu, Inti Zlobec, Maxime Lafarge +2

Due to the heterogeneity of real-world data, the widely accepted independent and identically distributed (IID) assumption has been criticized in recent studies on causality. In thi…

cs.CV2021

Rotation Invariance and Extensive Data Augmentation: a strategy for the Mitosis Domain Generalization (MIDOG) Challenge

Maxime W. Lafarge, Viktor H. Koelzer

Automated detection of mitotic figures in histopathology images is a challenging task: here, we present the different steps that describe the strategy we applied to participate in…

eess.IV2020★ 6 cited

Orientation-Disentangled Unsupervised Representation Learning for Computational Pathology

Maxime W. Lafarge, Josien P. W. Pluim, Mitko Veta

Unsupervised learning enables modeling complex images without the need for annotations. The representation learned by such models can facilitate any subsequent analysis of large im…

cs.CV2020

Roto-Translation Equivariant Convolutional Networks: Application to Histopathology Image Analysis

Maxime W. Lafarge, Erik J. Bekkers, Josien P. W. Pluim +2

Rotation-invariance is a desired property of machine-learning models for medical image analysis and in particular for computational pathology applications. We propose a framework t…

cs.CV2018

Roto-Translation Covariant Convolutional Networks for Medical Image Analysis

Erik J Bekkers, Maxime W Lafarge, Mitko Veta +3

We propose a framework for rotation and translation covariant deep learning using group convolutions. The group product of the special Euclidean motion group descri…

cs.CV2018

Inferring a Third Spatial Dimension from 2D Histological Images

Maxime W. Lafarge, Josien P. W. Pluim, Koen A. J. Eppenhof +2

Histological images are obtained by transmitting light through a tissue specimen that has been stained in order to produce contrast. This process results in 2D images of the specim…

cs.CV2017★ 23 cited

Adversarial training and dilated convolutions for brain MRI segmentation

Pim Moeskops, Mitko Veta, Maxime W. Lafarge +2

Convolutional neural networks (CNNs) have been applied to various automatic image segmentation tasks in medical image analysis, including brain MRI segmentation. Generative adversa…